Stephen M. Mount

Associate Professor
2109 H.J. Patterson Hall
(301) 405-6934
Education: 
Ph.D., Yale University
Biography: 

Stephen M. Mount is an associate professor in the Department of Cell Biology and Molecular Genetics with an appointment in the Center for Bioinformatics and Computational Biology.

He is a molecular geneticist interested in splice site selection during pre-mRNA splicing in eukaryotes, and his laboratory takes a genetic approach to this problem.

Mount received his doctorate from Yale University.

Publications

2010


Lin C-F, Mount SM, Jarmołowski A, Makałowski W.  2010.  Evolutionary dynamics of U12-type spliceosomal introns. BMC Evolutionary Biology. 10(1):47-47.

2009

2007


Mount SM, Gotea V, Lin C-F, Hernandez K, Makałowski W.  2007.  Spliceosomal small nuclear RNA genes in 11 insect genomes. RNARNA. 13(1):5-14.

Dogan RI, Getoor L, Wilbur WJ, Mount SM.  2007.  SplicePort--An interactive splice-site analysis tool. Nucleic Acids Research. 35(Web Server):W285-W291-W285-W291.

Clark AG, Eisen MB, Smith DR, Bergman CM, Oliver B, Markow TA, Kaufman TC, Kellis M, Gelbart W, Iyer VN et al..  2007.  Evolution of genes and genomes on the Drosophila phylogeny. Nature. 450(7167):203-218.

2006


Campbell MA, Haas BJ, Hamilton JP, Mount SM, Buell RC.  2006.  Comprehensive analysis of alternative splicing in rice and comparative analyses with Arabidopsis. BMC Genomics. 7(1):327-327.

2005


Hochheiser H, Baehrecke EH, Mount SM, Shneiderman B.  2005.  Dynamic Querying for Pattern Identification in Microarray and Genomic Data (2003). Institute for Systems Research Technical Reports.

2004


Salz HK, Mancebo RSY, Nagengast AA, Speck O, Psotka M, Mount SM.  2004.  The Drosophila U1-70K Protein Is Required for Viability, but Its Arginine-Rich Domain Is Dispensable. GeneticsGenetics. 168(4):2059-2065.

Roberts M, Hayes W, Hunt BR, Mount SM, Yorke JA.  2004.  Reducing storage requirements for biological sequence comparison. BioinformaticsBioinformatics. 20(18):3363-3369.

2003


Haas BJ, Delcher AL, Mount SM, Wortman JR, Jr R SK, Hannick LI, Maiti R, Ronning CM, Rusch DB, Town CD et al..  2003.  Improving the Arabidopsis genome annotation using maximal transcript alignment assemblies. Nucleic Acids ResearchNucl. Acids Res.. 31(19):5654-5666.

Hochheiser H, Baehrecke EH, Mount SM, Shneiderman B.  2003.  Dynamic querying for pattern identification in microarray and genomic data. 2003 International Conference on Multimedia and Expo, 2003. ICME '03. Proceedings. 3:III-453-6vol.3-III-453-6vol.3.

2002


Mount SM, Chang C.  2002.  Evidence for a Plastid Origin of Plant Ethylene Receptor Genes. Plant PhysiologyPlant Physiol.. 130(1):10-14.

2001

2000


Mount SM, Salz HK.  2000.  Pre-Messenger RNA Processing Factors in the Drosophila Genome. The Journal of Cell BiologyJ Cell Biol. 150(2):F37-F44-F37-F44.

Mount SM.  2000.  Genomic Sequence, Splicing, and Gene Annotation. American Journal of Human GeneticsAm J Hum Genet. 67(4):788-792.

1999

1997

1996


Mount SM.  1996.  AT-AC Introns—An ATtACk on Dogma. ScienceScience. 271(5256):1690-1692.

Peculis BA, Mount SM.  1996.  Ribosomal RNA: Small nucleolar RNAs make their mark. Current Biology. 6(11):1413-1415.

1995

1994


Maroni G, Mount SM, Cavener DR, Cavener BA, Sharp PM, Lloyd AT, Schaeffer SW.  1994.  An Atlas of Drosophila Genes: Sequences and Molecular Features. Journal of Heredity. 85(6):495-496.

Lo PC, Roy D, Mount SM.  1994.  Suppressor U1 snRNAs in Drosophila.. GeneticsGenetics. 138(2):365-378.

1993


Guo M, Lo PC, Mount SM.  1993.  Species-specific signals for the splicing of a short Drosophila intron in vitro.. Molecular and Cellular BiologyMol. Cell. Biol.. 13(2):1104-1118.

1992


Mount SM, Burks C, Herts G, Stormo GD, White O, Fields C.  1992.  Splicing signals in Drosophila: intron size, information content, and consensus sequences. Nucleic Acids ResearchNucl. Acids Res.. 20(16):4255-4262.

1991


Kurkulos M, Weinberg JM, Pepling ME, Mount SM.  1991.  Polyadenylylation in copia requires unusually distant upstream sequences. Proceedings of the National Academy of SciencesPNAS. 88(8):3038-3042.

1990


Pepling M, Mount SM.  1990.  Sequence of a cDNA from the Drosophila melanogaster white gene.. Nucleic Acids ResearchNucleic Acids Res. 18(6):1633-1633.

1988

1987


Mount SM.  1987.  Sequence similarity. Nature. 325(6104):487-487.

1985

1984

1983


Steitz JA, Wolin SL, Rinke J, Pettersson I, Mount SM, Lerner EA, Hinterberger M, Gottlieb E.  1983.  Small Ribonucleoproteins from Eukaryotes: Structures and Roles in RNA Biogenesis. Cold Spring Harbor Symposia on Quantitative BiologyCold Spring Harb Symp Quant Biol. 47:893-900.

Mount SM, Pettersson I, Hinterberger M, Karmas A, Steitz JA.  1983.  The U1 small nuclear RNA-protein complex selectively binds a 5′ splice site in vitro. Cell. 33(2):509-518.

1982


Mount SM.  1982.  A catalogue of splice junction sequences. Nucleic Acids ResearchNucl. Acids Res.. 10(2):459-472.

Steitz JA, Berg C, Gottlieb E, Hardin JA, Hashimoto C, Hendrick JP, Hinterberger M, Krikeles M, Lerner MR, Mount SM.  1982.  Structure and function of small ribonucleoproteins from eukaryotic cells. Princess Takamatsu symposiaInt. Symp. Princess Takamatsu Cancer Res. Fund. 12:101-107.

1981


Dingermann T, Sharp S, Appel B, DeFranco D, Mount SM, Heiermann R, Pongs O, Söll D.  1981.  Transcription of cloned tRNA and 5S RNA genes in a Drosophila cell free extract. Nucleic Acids ResearchNucl. Acids Res.. 9(16):3907-3918.

1980


Lerner MR, Boyle JA, Mount SM, Wolin SL, Steitz JA.  1980.  Are snRNPs involved in splicing? Nature. 283(5743):220-224.