Genomic analysis of ICEVchBan8: An atypical genetic element in Vibrio cholerae

TitleGenomic analysis of ICEVchBan8: An atypical genetic element in Vibrio cholerae
Publication TypeJournal Articles
Year of Publication2012
AuthorsTaviani E, Spagnoletti M, Ceccarelli D, Haley BJ, Hasan NA, Chen A, Colombo MM, Huq A, Colwell RR
JournalFEBS Letters
Date Published2012///
ISBN Number0014-5793
KeywordsGenomic islands, Integrative conjugative elements, Lateral gene transfer, Vibrio cholerae
Abstract

Genomic islands (GIs) and integrative conjugative elements (ICEs) are major players in bacterial evolution since they encode genes involved in adaptive functions of medical or environmental importance. Here we performed the genomic analysis of ICEVchBan8, an unusual ICE found in the genome of a clinical non-toxigenic Vibrio cholerae O37 isolate. ICEVchBan8 shares most of its genetic structure with SXT/R391 ICEs. However, this ICE codes for a different integration/excision module is located at a different insertion site, and part of its genetic cargo shows homology to other pathogenicity islands of V. cholerae.

URLhttp://www.sciencedirect.com/science/article/pii/S0014579312002748
DOI10.1016/j.febslet.2012.03.064